RhoB in immflamation

A recent paper published in the Journal of Cell Biology by Beatriz Marcos-Ramiro, Jaime Millan and colleagues, addresses RhoB small GTPase function during inflammation. RhoB controls endothelial barrier in response to inflammatory cytokines by regulating Rac1 trafficking to the cell membrane and cell protrusion.

Reference: “RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border” Marcos-Ramiro et al. Journal of Cell Biology. 213 (3): 385, 2016

RhoB

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